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Fluorescent Protein Literature Sources

Fluorescent proteins (FPs) derived from marine organisms have revolutionized cellular and molecular biology. They serve as versatile fusion tags, enabling researchers to track protein behavior, localization, and dynamics in living cells in real time. Among these, green fluorescent protein (GFP) and its variants are the most widely used. GFP can be fused to virtually any protein of interest without disrupting its folding or function, allowing researchers to visualize previously uncharacterized proteins or study the dynamics of known proteins in various cellular processes.

This section provides a curated set of literature sources, including review articles and original research reports, covering the discovery, engineering, and applications of fluorescent proteins. These references are invaluable for understanding the principles, advancements, and current trends in FP-based imaging.

Key Review Articles

  1. Chudakov, D.M., et al. (2010). Fluorescent proteins and their applications in imaging living cells and tissues. Physiological Reviews, 90(3), 1103–1163.

    PDF Link

  2. Tsien, R.Y. (1998). The green fluorescent protein. Annual Review of Biochemistry, 67, 509–544.

    PDF Link

  3. Shaner, N.C., et al. (2005). Advances in fluorescent protein technology. Journal of Cell Science, 118, 4247–4260.

    Open Access

  4. Day, R.N., & Davidson, M.W. (2009). The fluorescent protein palette: Tools for cellular imaging. Chemical Society Reviews, 38, 2887–2921.

    PDF Link

Original Research Articles

  1. Prasher, D.C., et al. (1992). Primary structure of the Aequorea victoria green-fluorescent protein. Gene, 111, 229–233.

    ScienceDirect PDF

  2. Cormack, B.P., et al. (1996). Yeast-enhanced green fluorescent protein for gene expression studies in Saccharomyces cerevisiae. Gene, 173, 33–38.

    PDF Link

  3. Heim, R., et al. (1995). Improved green fluorescence. Nature, 373, 663–664.

    Nature Link

  4. Shaner, N.C., et al. (2004). Improved monomeric red, orange, and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nature Biotechnology, 22, 1567–1572.

    Nature Biotechnology PDF

Databases and Resources